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Wild Quinine has yet to make a splash in home gardens, but it has many virtues making it worthy of consideration: Easy to grow, long-blooming, attractive to many pollinators, an upright form and excellent foliage, a pleasant medicinal fragrance, and dried flowers for arrangements.
Cultivation
Wild Quinine is said to grow in full sun or part shade, depending on the source. In very hot locations, part shade is likely to suit it best, but in most places in Floyd it should do quite well in a full sun garden spot. Well-drained soil seems to be the only consistent requirement, making most of Floyd’s soils suitable in theory. But the beautiful foliage and long-flowering habit will probably need decent moisture to show their full potential. This clump-forming tap-rooted perennial self-sows readily, so plant with this in mind. Combine with Liatris, Monarda, Echinacea and Black-Eyed Susan for a beautiful late summer show.

Ecology
Wild Quinine is said to attract many pollinators over its long bloom period, and to make a nice addition to prairie plantings both for its nectar production and self-sowing habit. Prairie Moon Nursery includes among those pollinators, “Halictine bees, wasps, flies, and beetles.” Although it can be found growing in Virginia’s protected barrens, it prefers high quality habitats and is usually absent from disturbed sites, as suggested by its C-value of 6.
Virginia Heritage Communities
The Virginia Heritage Communities represent relatively intact mature ecosystems, as opposed to roadsides and fields which would be categorized as disturbed or even ruderal. Or as opposed to forests that are growing back from having been logged, sometimes called secondary growth forests. In the Heritage Communities, Parthenium integrifolium tends to be associated with outcrop barrens, not because it prefers these growing conditions, but because Southwest Virginia’s mature ecosystems are usually dense forests where this herb would not find enough sunlight to grow. The handful of mature ecosystems in this part of Appalachia where Wild Quinine might find a toehold include the barrens.


Human Uses
According to Wikipedia: “The leaves of the plant contain tannins and the plant was used for medicinal and veterinary purposes by Native Americans. The Catawba people used it as a poultice to treat burns. The ashes were applied to horses with “sore backs”. The roots were made into a tea to treat dysentery.”
Read More
http://vaplantatlas.org/index.php?do=plant&plant=2219&search=Search
https://en.wikipedia.org/wiki/Parthenium_integrifolium
https://www.wildflower.org/plants/result.php?id_plant=PAIN3
https://plants.ces.ncsu.edu/plants/parthenium-integrifolium/
https://www.missouribotanicalgarden.org/PlantFinder/PlantFinderDetails.aspx?taxonid=277453
https://www.gardenia.net/plant/parthenium-integrifolium
https://www.prairiemoon.com/parthenium-integrifolium-wild-quinine-prairie-moon-nursery.html
https://www.prairienursery.com/wild-quinine-parthenium-integrifolium.html
http://www.newmoonnursery.com/plant/Parthenium-integrifolium